Average protein density is a molecular-weight-dependent function
نویسندگان
چکیده
منابع مشابه
Molecular Density Function Perturbations
Studies performed at single-cell resolution have demonstrated the physiological 9 significance of cell-to-cell variability. Various types of mathematical models and systems analyses 10 of biological networks have further been used to gain a better understanding of the sources and 11 regulatory mechanisms of such variability. In this work, we present a novel sensitivity analysis 12 method, calle...
متن کاملDetection of low molecular weight derivatives of cyclin E1 is a function of cyclin E1 protein levels in breast cancer.
Cyclin E1 regulates the initiation of the S phase program in the mammalian cell division cycle. In normal cells, cyclin E1 protein expression is tightly controlled through a combination of transcriptional and proteolytic regulatory processes. However, in many types of human tumor, cyclin E1 expression is frequently dysregulated, including overexpression, nonperiodic expression relative to cell ...
متن کاملPredicting Protein Molecular Function
Predicting Protein Molecular Function by Barbara Elizabeth Engelhardt Doctor of Philosophy in Computer Science and the Designated Emphases in Computational and Genomic Biology and Communication, Computation, and Statistics University of California, Berkeley Professor Michael I. Jordan, Chair The number of known nucleotide sequences encoding proteins is growing at an extraordinarily fast rate du...
متن کاملTime-dependent density functional molecular dynamics simulation
We present a scheme to simulate the coupled electron-ion dynamics within the density functional theory. In our scheme, letting the electrons and ions follow the time-dependent Kohn-Sham equation and the Newton equation, respectively, ultrafast dynamics induced by electronic excitation is investigated. We first show approximations made in that simulation to clarify the advantage and limitation o...
متن کاملIs impaired renal function a contraindication to the use of low-molecular-weight heparin?
BACKGROUND Because of the risk of accumulation of anticoagulant effect, it has been suggested that patients with a creatinine clearance of 30 mL/min or less (< or =0.50 mL/s) should be excluded from treatment with low-molecular-weight (LMW) heparin, or have anti-factor Xa heparin level monitoring performed. OBJECTIVE To assess the appropriateness of this recommendation. METHODS We performed...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Protein Science
سال: 2009
ISSN: 0961-8368
DOI: 10.1110/ps.04688204